More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/PSD95 antibody

PSD95 antibody

Research Use Only
GTX133091
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDlg4
Price on request
Packing Size
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    PSD95 antibody
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.39 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID13385
  • Target name
    Dlg4
  • Target description
    discs large MAGUK scaffold protein 4
  • Target synonyms
    discs large homolog 4; discs, large homolog 4; disks large homolog 4; Dlgh; Dlgh4; postsynaptic density protein 95; PSD; PSD-; PSD95; PSD-95; PSD-95 alpha 2b; PSD-95 beta; SA; SAP90; SAP-90; SAP90A; synapse-associated protein 90
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Low-Intensity Focused Ultrasound Stimulation Ameliorates Working Memory Dysfunctions in Vascular Dementia Rats via Improving Neuronal Environment. Wang F et al., 2022, Front Aging Neurosci
    Read more
  • Maternal Cigarette Smoke Exposure Exaggerates the Behavioral Defects and Neuronal Loss Caused by Hypoxic-Ischemic Brain Injury in Female Offspring. Huang T et al., 2022, Front Cell Neurosci
    Read more
  • In vitro modulation of Schwann cell behavior by VEGF and PDGF in an inflammatory environment. Basu S et al., 2022 Jan 13, Sci Rep
    Read more
  • Blood-Brain Barrier Disruption Increases Amyloid-Related Pathology in TgSwDI Mice. Abdallah IM et al., 2021 Jan 27, Int J Mol Sci
    Read more
  • Rapid differentiation of human dental pulp stem cells to neuron-like cells by high K+ stimulation. Kogo Y et al., 2020, Biophys Physicobiol
    Read more
  • Inhibition of Colony-Stimulating Factor 1 Receptor by PLX3397 Prevents Amyloid Beta Pathology and Rescues Dopaminergic Signaling in Aging 5xFAD Mice. Son Y et al., 2020 Aug 3, Int J Mol Sci
    Read more
  • Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype. Hou B et al., 2020 May 15, Cell Death Dis
    Read more
  • Breviscapine exerts neuroprotective effects through multiple mechanisms in APP/PS1 transgenic mice. Li Z et al., 2020 May, Mol Cell Biochem
    Read more
  • Amylin and pramlintide modulate gamma-secretase level and APP processing in lipid rafts. Mousa YM et al., 2020 Feb 28, Sci Rep
    Read more
  • Activation of alpha7 nAChR by PNU-282987 improves synaptic and cognitive functions through restoring the expression of synaptic-associated proteins and the CaM-CaMKII-CREB signaling pathway. Wang XL et al., 2020 Jan 6, Aging (Albany NY)
    Read more