PSD95 antibody
GTX133091
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetDlg4
Overview
- SupplierGeneTex
- Product NamePSD95 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.24 mg/ml
- ConjugateUnconjugated
- Gene ID13385
- Target nameDlg4
- Target descriptiondiscs large MAGUK scaffold protein 4
- Target synonymsDlgh4, PSD-95, PSD95, SAP90, SAP90A, disks large homolog 4, PSD-95 alpha 2b, PSD-95 beta, SAP-90, discs large homolog 4, discs, large homolog 4, postsynaptic density protein 95, synapse-associated protein 90
- HostRabbit
- IsotypeIgG
- Protein IDQ62108
- Protein NameDisks large homolog 4
- Scientific DescriptionInteracts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chiu YS, Wu KJ, Yu SJ, et al. Peptide immunization against the C-terminal of alpha-synuclein reduces locomotor activity in mice overexpressing alpha-synuclein. PLoS One. 2023,18(9):e0291927. doi: 10.1371/journal.pone.0291927Read this paper
- Wang L, Ling H, He H, et al. Dysfunctional synaptic pruning by microglia correlates with cognitive impairment in sleep-deprived mice: Involvement of CX3CR1 signaling. Neurobiol Stress. 2023,25:100553. doi: 10.1016/j.ynstr.2023.100553Read this paper
- Wang F, Wang Q, Wang L, et al. Low-Intensity Focused Ultrasound Stimulation Ameliorates Working Memory Dysfunctions in Vascular Dementia Rats via Improving Neuronal Environment. Front Aging Neurosci. 2022,14:814560. doi: 10.3389/fnagi.2022.814560Read this paper
- Huang T, Huang X, Li H, et al. Maternal Cigarette Smoke Exposure Exaggerates the Behavioral Defects and Neuronal Loss Caused by Hypoxic-Ischemic Brain Injury in Female Offspring. Front Cell Neurosci. 2022,16:818536. doi: 10.3389/fncel.2022.818536Read this paper
- Ren J, Zhang S, Wang X, et al. MEF2C ameliorates learning, memory, and molecular pathological changes in Alzheimer’s disease in vivo and in vitro. Acta Biochim Biophys Sin (Shanghai). 2022,54(1):77-90. doi: 10.3724/abbs.2021012Read this paper
- Basu S, Choudhury IN, Nazareth L, et al. In vitro modulation of Schwann cell behavior by VEGF and PDGF in an inflammatory environment. Sci Rep. 2022,12(1):662. doi: 10.1038/s41598-021-04222-7Read this paper
- Abdallah IM, Al-Shami KM, Yang E, et al. Blood-Brain Barrier Disruption Increases Amyloid-Related Pathology in TgSwDI Mice. Int J Mol Sci. 2021,22(3). doi: 10.3390/ijms22031231Read this paper
- Kogo Y, Seto C, Totani Y, et al. Rapid differentiation of human dental pulp stem cells to neuron-like cells by high K(+) stimulation. Biophys Physicobiol. 2020,17:132-139. doi: 10.2142/biophysico.BSJ-2020023Read this paper
- Son Y, Jeong YJ, Shin NR, et al. Inhibition of Colony-Stimulating Factor 1 Receptor by PLX3397 Prevents Amyloid Beta Pathology and Rescues Dopaminergic Signaling in Aging 5xFAD Mice. Int J Mol Sci. 2020,21(15). doi: 10.3390/ijms21155553Read this paper
- Hou B, Zhang Y, Liang P, et al. Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype. Cell Death Dis. 2020,11(5):377. doi: 10.1038/s41419-020-2565-2Read this paper
Datasheet
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