PSMC2 Polyclonal Antibody

Reddot Biotech

PSMC2 Polyclonal Antibody

5

Western Blot, ELISA

Research Use Only

Polyclonal

0.3 mg/ml

Unconjugated

PSMC2

proteasome 26S subunit, ATPase 2

MSS1, Nbla10058, RPT1, S7, 26S proteasome regulatory subunit 7, 26S protease regulatory subunit 7, 26S proteasome AAA-ATPase subunit RPT1, mammalian suppressor of sgv-1 of yeast, protease 26S subunit 7, proteasome (prosome, macropain) 26S subunit, ATPase, 2, putative protein product of Nbla10058, testis secretory sperm-binding protein Li 197a

Rabbit

IgG

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity.

-20°C

12352203