Western Blot analysis of Hela cell and Mouse lung tissue using PTCH1 Polyclonal Antibody at dilution of 1:900
Western Blot analysis of Hela cell and Mouse lung tissue using PTCH1 Polyclonal Antibody at dilution of 1:900
PTCH1 Polyclonal Antibody
E-AB-10571
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePTCH1 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.5mg/ml
- Scientific DescriptionThis gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
- UNSPSC12352203