Immunofluorescence analysis of C6 cells using PTPN22 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
PTPN22 Polyclonal Antibody
E-AB-60305
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePTPN22 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
- UNSPSC12352203