Pyridomycin [18791-21-4]

BioViotica

Pyridomycin [18791-21-4]

10

18791-21-4

Research Use Only

>98%

C27H32N4O8

540.6

Chemical. CAS: 18791-21-4. Formula: C27H32N4O8. MW: 540.6. Isolated from Streptomyces sp. Cyclodepsipeptide antibiotic. Unusual 12-membered macrocyclic depsipeptide comprises three unique subunits incorporating two substituted pyridines. Potent antitubercular agent. Inhibitor of NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis. Shown to be active against isoniazid-resistant mycobacteria. - Cyclodepsipeptide antibiotic. Unusual 12-membered macrocyclic depsipeptide comprises three unique subunits incorporating two substituted pyridines. Potent antitubercular agent. Inhibitor of NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis. Shown to be active against isoniazid-resistant mycobacteria.

CC\C(C)=C1/OC(=O)[C@H](C)[C@H](O)[C@H](CC2=CC=CN=C2)NC(=O)[C@@H](NC(=O)C2=C(O)C=CC=N2)[C@@H](C)OC1=O

2°C to 8°C

12352200