Pyridone 6 [457081-03-7]

TargetMol Chemicals

Pyridone 6

9

457081-03-7

Chemical

Research Use Only

Pyridone 6

98.70%

C18H16FN3O

309.34

Pyridone 6 (JAK Inhibitor)(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM) for other protein tyrosine kinases.

3 years

CC(C)(C)c1nc2c([nH]1)c1ccc(F)cc1c1c2cc[nH]c1=O

-20°C

12352200