IHC-P analysis of human lung carcinoma tissue using GTX87071 Pyruvate Carboxylase antibody. The picture on the right is blocked with the synthesized peptide.
IHC-P analysis of human lung carcinoma tissue using GTX87071 Pyruvate Carboxylase antibody. The picture on the right is blocked with the synthesized peptide.
Pyruvate Carboxylase antibody
GTX87071
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPC
Overview
- SupplierGeneTex
- Product NamePyruvate Carboxylase antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500~1:1000. IHC-P: 1:50~1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5091
- Target namePC
- Target descriptionpyruvate carboxylase
- Target synonymsPCB; pyruvate carboxylase, mitochondrial; pyruvic carboxylase
- HostRabbit
- IsotypeIgG
- Protein IDP11498
- Protein NamePyruvate carboxylase, mitochondrial
- Scientific DescriptionThis gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5 UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Edoxaban improves atrial fibrillation and thromboembolism through regulation of the Wnt-beta-induced PI3K/ATK-activated protein C system. Shan X et al., 2019 May, Exp Ther MedRead more