
WB analysis of mouse liver lysate using GTX88823 Pyruvate Carboxylase antibody, Internal. Dilution : 0.03microg/ml Loading : 35microg protein in RIPA buffer
Pyruvate Carboxylase antibody, Internal
GTX88823
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPC
Overview
- SupplierGeneTex
- Product NamePyruvate Carboxylase antibody, Internal
- Delivery Days Customer7
- Application Supplier NoteWB: 0.03-0.1microg/ml. IHC-P: 5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID5091
- Target namePC
- Target descriptionpyruvate carboxylase
- Target synonymsPCB; pyruvate carboxylase, mitochondrial; pyruvic carboxylase
- HostGoat
- IsotypeIgG
- Protein IDP11498
- Protein NamePyruvate carboxylase, mitochondrial
- Scientific DescriptionThis gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5 UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203