Pyruvate Kinase (liver/RBC) antibody
![Research Use Only](static/images/certificates/ruo.jpg)
GTX111536
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetPKLR
Overview
- SupplierGeneTex
- Product NamePyruvate Kinase (liver/RBC) antibody
- Delivery Days Customer9
- Antibody SpecificityThis antibody is raised against the R-Type isoform. Based on a BLAST result, it may also react with the L-Type isoform.
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID5313
- Target namePKLR
- Target descriptionpyruvate kinase L/R
- Target synonymsPK1; PKL; PKRL; pyruvate kinase 1; pyruvate kinase isozyme R/L; pyruvate kinase isozymes L/R; pyruvate kinase isozymes R/L; pyruvate kinase PKLR; pyruvate kinase type L; pyruvate kinase, liver and blood cell; pyruvate kinase, liver and RBC; red cell/liver pyruvate kinase; RPK; R-type/L-type pyruvate kinase
- HostRabbit
- IsotypeIgG
- Protein IDP30613
- Protein NamePyruvate kinase PKLR
- Scientific DescriptionThe protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Dietary supplementation with myo-inositol reduces hepatic triglyceride accumulation and expression of both fructolytic and lipogenic genes in rats fed a high-fructose diet. Shimada M et al., 2017 Nov, Nutr ResRead more