More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/(R)-CR8 (trihydrochloride)

(R)-CR8 (trihydrochloride)

HY-18340A
MedChem Express
CAS Number1786438-30-9
DownloadMSDS
Product group Chemicals
Estimated Purity98.95
Molecular Weight540.92
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    MedChem Express
  • Product Name
    (R)-CR8 (trihydrochloride) [1786438-30-9]
  • Delivery Days Customer
    10
  • CAS Number
    1786438-30-9
  • Certification
    Research Use Only
  • Estimated Purity
    98.95
  • Molecular Formula
    C24H32Cl3N7O
  • Molecular Weight
    540.92
  • Scientific Description
    (R)-CR8 (CR8) trihydrochloride, a second-generation analog of Roscovitine, is a potent CDK1/2/5/7/9 inhibitor. (R)-CR8 trihydrochloride inhibits CDK1/cyclin B ( IC 50 =0.09 microM), CDK2/cyclin A (0.072 microM), CDK2/cyclin E (0.041 microM), CDK5/p25 (0.11 microM), CDK7/cyclin H (1.1 microM), CDK9/cyclin T (0.18 microM) and CK1delta/epsilon (0.4 microM). (R)-CR8 trihydrochloride induces apoptosis and has neuroprotective effect [1] [2] . (R)-CR8 trihydrochloride acts as a molecular glue degrader that depletes cyclin K [3] .
  • SMILES
    CC[C@@H](NC1=NC(NCC2=CC=C(C3=NC=CC=C3)C=C2)=C4N=CN(C(C)C)C4=N1)CO.[H]Cl.[H]Cl.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

Related products

Product group Chemicals
AbMole BioScience
(R)-CR8 trihydrochlorideM21148
CAS Number1786438-30-9
Molecular Weight468
  • SizePrice
Product group Chemicals
Biorbyt
(R)-CR8 trihydrochlorideORB1708758
CAS Number1786438-30-9
Estimated Purity98%
Molecular Weight540.92
  • SizePrice
(R)-CR8 trihydrochloride [1786438-30-9]
Product group Chemicals
TargetMol Chemicals
(R)-CR8 trihydrochloride [1786438-30-9]T12617
CAS Number1786438-30-9
Estimated Purity99.33%
Molecular Weight540.92
  • SizePrice