Bio-Connect

(R)-CR8 trihydrochloride

M21148
AbMole BioScience
CAS Number1786438-30-9
Product group Chemicals
Molecular Weight468
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    AbMole BioScience
  • Product Name
    (R)-CR8 trihydrochloride
  • Delivery Days Customer
    9
  • CAS Number
    1786438-30-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C24H30ClN7O
  • Molecular Weight
    468
  • Scientific Description
    (R)-CR8 trihydrochloride, one of the isomers of CR8, is a potent CDK1/2/5/7/9 inhibitor with anti-proliferative and pro-apoptotic effects on CML cell lines. (R)-CR8 trihydrochloride inhibited CDK1/cyclin B (IC50=0.09 uM), CDK2/cyclin A (0.072 uM), CDK2/cyclin E (0.041 uM), CDK5/p25 (0.11 uM), CDK7/cyclin H (1.1 uM ), CDK9/cyclin T (0.18 uM) and CK1delta/epsilon (0.4 uM).
  • SMILES
    Cl.Cl.Cl.CCC(CO)NC1=NC(=C2N=C[N](C(C)C)C2=N1)NCC3=CC=C(C=C3)C4=CC=CC=N4
  • Storage Instruction
    2-8°C, dry, sealed
  • UNSPSC
    12352200

Related products

Product group Chemicals
MedChem Express
CAS Number1786438-30-9
Estimated Purity98.95
Molecular Weight540.92
  • SizePrice
Product group Chemicals
Biorbyt
CAS Number1786438-30-9
Estimated Purity98%
Molecular Weight540.92
  • SizePrice
(R)-CR8 trihydrochloride [1786438-30-9]
Product group Chemicals
TargetMol Chemicals
CAS Number1786438-30-9
Estimated Purity99.33%
Molecular Weight540.92
  • SizePrice