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(R)-(-)-Gossypol acetic acid [866541-93-7]

(R)-(-)-Gossypol acetic acid [866541-93-7]

Research Use Only
T6396
TargetMol Chemicals
CAS Number866541-93-7
Product group Chemicals
Estimated Purity0.9673
Molecular Weight578.61
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    (R)-(-)-Gossypol acetic acid
  • Delivery Days Customer
    4
  • CAS Number
    866541-93-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    (R)-(-)-Gossypol acetic acid
  • Estimated Purity
    0.9673
  • Molecular Formula
    C30H30O8 C2H4O2
  • Molecular Weight
    578.61
  • Scientific Description
    (R)-(-)-Gossypol acetic acid (AT101 acetate), the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL, and Mcl-1 with Ki values of 0.32 microM, 0.48 microM, and 0.18 microM, respectively; it does not inhibit the BIR3 domain or BID. [Phase 2]
  • Shelf life instruction
    3 years
  • SMILES
    CC(O)=O.CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200