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(R)-(-)-JQ1 Enantiomer

T19618
TargetMol Chemicals
CAS Number1268524-71-5
Product group Chemicals
Molecular Weight456.99
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    (R)-(-)-JQ1 Enantiomer
  • Delivery Days Customer
    4
  • CAS Number
    1268524-71-5
  • Category Supplier
    Chemical
  • Chemical Name
    (R)-(-)-JQ1 Enantiomer
  • Molecular Formula
    C23H25ClN4O2S
  • Molecular Weight
    456.99
  • Scientific Description
    (R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)
  • Shelf life instruction
    3 years
  • SMILES
    CC=1C2=C(N3C([C@@H](CC(OC(C)(C)C)=O)N=C2C4=CC=C(Cl)C=C4)=NN=C3C)SC1C
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Filippakopoulos, et al. Selective inhibition of BET bromodomains. Nature. 2010 Dec 23;468(7327):1067-73.