(R)-Roscovitine

MedChem Express

(R)-Roscovitine [186692-46-6]

5

186692-46-6

Research Use Only

99.53

C19H26N6O

354.45

(R)-Roscovitine (Seliciclib) is an orally bioavailable and selective CDKs inhibitor with IC 50 s of 0.2 microM, 0.65 microM, and 0.7 microM for CDK5 , Cdc2 , and CDK2 , respectively.

OC[C@H](NC1=NC(NCC2=CC=CC=C2)=C3C(N(C=N3)C(C)C)=N1)CC

-20°C,2°C to 8°C

12352200