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R406 besylate

M14916
AbMole BioScience
CAS Number841290-81-1
Product group Chemicals
Molecular Weight628.63
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    R406 besylate
  • Delivery Days Customer
    9
  • CAS Number
    841290-81-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C22H23FN6O5.C6H6O3S
  • Molecular Weight
    628.63
  • Scientific Description
    R406 is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value.
  • SMILES
    COC1=C(OC)C(=CC(=C1)NC2=NC(=C(F)C=N2)NC3=NC4=C(OC(C)(C)C(=O)N4)C=C3)OC.O[S](=O)(=O)C5=CC=CC=C5
  • Storage Instruction
    2-8°C, dry, sealed
  • UNSPSC
    12352200

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