R547

MedChem Express

R547 [741713-40-6]

10

741713-40-6

Research Use Only

99.57

C18H21F2N5O4S

441.45

R547 is a potent, selective and orally active ATP-competitive CDK inhibitor, with Kis of 2 nM, 3 nM and 1 nM for CDK1/cyclin B, CDK2/cyclin E and CDK4/cyclin D1, respectively[1][2][3][4][5].

O=S(N1CCC(NC2=NC(N)=C(C(C3=C(C(F)=CC=C3OC)F)=O)C=N2)CC1)(C)=O

-20°C,2°C to 8°C

12352200