R547 [741713-40-6]

TargetMol Chemicals

R547 [741713-40-6]

9

741713-40-6

Chemical

Research Use Only

R547

99.84%

C18H21F2N5O4S

441.45

R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3alpha/beta, while inactive to other kinases. Phase 1.

3 years

COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(CC2)S(C)(=O)=O)nc1N

-20°C

12352200