R788 disodium hexahydrate

Biorbyt

R788 disodium hexahydrate [914295-16-2]

10

914295-16-2

Research Use Only

C23H24FN6Na2O9P.6H2O

732.51

Fostamatinib (R788) is a prodrug of the active metabolite R406, which is a potent, ATP-competitive inhibitor of Syk kinase with Ki/IC50 of 30/41 nM.

COC1=C(OC)C(OC)=CC(NC2=NC(NC3=NC4N(C(C(C)(C)OC=4C=C3)=O)COP(O)(O)=O)=C(F)C=N2)=C1.[NaH].O

12352200