Western Blot Positive WB detected in: Mouse kidney tissue, Mouse liver tissue, Rat lung tissue All lanes: RAB5A antibody at 3ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 24, 23 kDa Observed band size: 24 kDa
Western Blot Positive WB detected in: Mouse kidney tissue, Mouse liver tissue, Rat lung tissue All lanes: RAB5A antibody at 3ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 24, 23 kDa Observed band size: 24 kDa
RAB5A Antibody
CSB-PA019213EA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRAB5A
Overview
- SupplierCusabio
- Product NameRAB5A Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5868
- Target nameRAB5A
- Target descriptionRAB5A, member RAS oncogene family
- Target synonymsRAB5; RAS-associated protein RAB5A; ras-related protein Rab-5A
- HostRabbit
- IsotypeIgG
- Protein IDP20339
- Protein NameRas-related protein Rab-5A
- Scientific DescriptionThe small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed:22660413). Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3 (By similarity).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203