Rabbit anti Human DNA Topoisomerase 1
X2732P
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTOP1
Overview
- SupplierNordic-MUbio
- Product NameRabbit anti Human DNA Topoisomerase 1
- Delivery Days Customer7
- Application Supplier NoteAntibody can be used for immunohistochemistry at 5-10 microg/ml on paraffin-embedded tissues. Optimal concentration should be evaluated by serial dilutions.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierImmunohistochemistry (paraffin);Immunohistochemistry (paraffin)
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ClonalityPolyclonal
- Gene ID7150
- Target nameTOP1
- Target descriptionDNA topoisomerase I
- Target synonymsDNA topoisomerase 1; Scl-70 antigen; TOPI; topoisomerase (DNA) I; type I DNA topoisomerase
- HostRabbit
- Protein IDP11387
- Protein NameDNA topoisomerase 1
- Shelf life instructionSee expiration date on vial
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteSynthetic peptide made to human DNA Topoisomerase 1
- UNSPSC12352203
References
- 1. Oddou, P., et al. 'Monoclonal antibodies neutralizing mammalian DNA topoisomerase I activity.' Eur. J. Biochem. 1988, 177, 523-529 2. Redinbo, M.R., et al. 'Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA.' Biochemistry 2000, 39, 6832-6840 3. Eisenreich, A., et al. 'Cdc2-like kinases and DNA topoisomerase I regulate alternative splicing of tissue factor in human endothelial cells.' Circ. Res. 2009, 104, 589-599