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Rabbit anti Human ERCC1 (DNA excision repair protein)

Research Use Only
X2734P
Nordic-MUbio
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetERCC1
Price on request
100 ug
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Nordic-MUbio
  • Product Name
    Rabbit anti Human ERCC1 (DNA excision repair protein)
  • Delivery Days Customer
    7
  • Application Supplier Note
    This antibody can be used for Western blotting (5-10 microg/ml) and immunohistochemistry on formalin/paraffin sections (5-10 microg/ml). Optimal concentration should be evaluated by serial dilutions.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Applications Supplier
    Western Blotting;Immunohistochemistry (paraffin);Western Blotting;Immunohistochemistry (paraffin)
  • Category Supplier
    Primary antibodies
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Gene ID2067
  • Target name
    ERCC1
  • Target description
    ERCC excision repair 1, endonuclease non-catalytic subunit
  • Target synonyms
    COFS4; DNA excision repair protein ERCC-1; excision repair cross-complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); RAD10; UV20
  • Host
    Rabbit
  • Protein IDP07992
  • Protein Name
    DNA excision repair protein ERCC-1
  • Scientific Description
    Excision Repair Cross Complementing protein-1; Nucleotide Excision Repair Protein
  • Shelf life instruction
    See expiration date on vial
  • Reactivity
    Human
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    Synthetic peptide derived from human ERCC1 protein
  • UNSPSC
    12352203

References

  • 1. Hayashi T, et al: ERCC1 mutations in UV-sensitive Chinese hamster ovary (CHO) cell lines. Mutat Res 1998;407(3):269-276. 2. de Laat WL, et al: DNA structural elements required for ERCC1-XPF endonuclease activity. J Biol Chem 1998;273(14):7835-7842. 3. de Laat WL, et al: Mapping of interaction domains between human repair proteins ERCC1 and XPF. Nucleic Acids Res 1998 Sep 15;26(18):4146-4152. 4. Lee-Kwon W, et al: Involvement of the Ras/extracellular signal-regulated kinase signalling pathway in the regulation of ERCC-1 mRNA levels by insulin. Biochem J 1998 Apr 15;331 ( Pt 2):591-597. 5. Lee-Kwon W, et al: Nucleotide excision repair is not required for the antiapoptotic function of insulin-like growth factor 1. Exp Cell Res 1998;241(2):458-466. 6. Li Q, Bostick-Bruton F, Reed E: Effect of interleukin-1 alpha and tumour necrosis factor- alpha on cisplatin-induced ERCC-1 mRNA expression in a human ovarian carcinoma cell line. Anticancer Res 1998;18(4A):2283-2287. 7. Li Q, Ding L, Yu JJ, Mu C, Tsang B, Bostick- Bruton F, Reed E: Cisplatin and phorbol ester independently induce ERCC-1 protein in human ovarian carcinoma cells. Int J Oncol 1998;13(5):987-992. 8. Lin YW, Kubota M, Koishi S, Sawada M, Usami I, Watanabe K, Akiyama Y: Analysis of mutations at the DNA repair genes in acute childhood leukaemia. Br J Haematol 1998;13(4):357-365. 9. Reed E: Platinum-DNA adduct, nucleotide excision repair and platinum based anti-cancer chemotherapy. Cancer Treat Rev 1998;24(5):331-344. 10. Rolig RL, Lowery MP, Adair GM, Nairn RS: Characterization and analysis of Chinese hamster ovary cell ERCC1 mutant alleles. Mutagenesis 1998;13(4):357-365. 11. Li Q, Tsang B, Bostick-Bruton F, Reed E: Modulation of excision repair cross complementation group 1 (ERCC-1) mRNA expression by pharmacological agents in human ovarian carcinoma cells. Biochem Pharmacol 1999;57(4):347-353. 12. Miura M, et al. Exp Cell Res 1996;226:126-132.