Rabbit anti Human ERCC1 (DNA excision repair protein)
X2734P
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetERCC1
Overview
- SupplierNordic-MUbio
- Product NameRabbit anti Human ERCC1 (DNA excision repair protein)
- Delivery Days Customer7
- Application Supplier NoteThis antibody can be used for Western blotting (5-10 microg/ml) and immunohistochemistry on formalin/paraffin sections (5-10 microg/ml). Optimal concentration should be evaluated by serial dilutions.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierWestern Blotting;Immunohistochemistry (paraffin);Western Blotting;Immunohistochemistry (paraffin)
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ClonalityPolyclonal
- Gene ID2067
- Target nameERCC1
- Target descriptionERCC excision repair 1, endonuclease non-catalytic subunit
- Target synonymsCOFS4; DNA excision repair protein ERCC-1; excision repair cross-complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); RAD10; UV20
- HostRabbit
- Protein IDP07992
- Protein NameDNA excision repair protein ERCC-1
- Scientific DescriptionExcision Repair Cross Complementing protein-1; Nucleotide Excision Repair Protein
- Shelf life instructionSee expiration date on vial
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteSynthetic peptide derived from human ERCC1 protein
- UNSPSC12352203
References
- 1. Hayashi T, et al: ERCC1 mutations in UV-sensitive Chinese hamster ovary (CHO) cell lines. Mutat Res 1998;407(3):269-276. 2. de Laat WL, et al: DNA structural elements required for ERCC1-XPF endonuclease activity. J Biol Chem 1998;273(14):7835-7842. 3. de Laat WL, et al: Mapping of interaction domains between human repair proteins ERCC1 and XPF. Nucleic Acids Res 1998 Sep 15;26(18):4146-4152. 4. Lee-Kwon W, et al: Involvement of the Ras/extracellular signal-regulated kinase signalling pathway in the regulation of ERCC-1 mRNA levels by insulin. Biochem J 1998 Apr 15;331 ( Pt 2):591-597. 5. Lee-Kwon W, et al: Nucleotide excision repair is not required for the antiapoptotic function of insulin-like growth factor 1. Exp Cell Res 1998;241(2):458-466. 6. Li Q, Bostick-Bruton F, Reed E: Effect of interleukin-1 alpha and tumour necrosis factor- alpha on cisplatin-induced ERCC-1 mRNA expression in a human ovarian carcinoma cell line. Anticancer Res 1998;18(4A):2283-2287. 7. Li Q, Ding L, Yu JJ, Mu C, Tsang B, Bostick- Bruton F, Reed E: Cisplatin and phorbol ester independently induce ERCC-1 protein in human ovarian carcinoma cells. Int J Oncol 1998;13(5):987-992. 8. Lin YW, Kubota M, Koishi S, Sawada M, Usami I, Watanabe K, Akiyama Y: Analysis of mutations at the DNA repair genes in acute childhood leukaemia. Br J Haematol 1998;13(4):357-365. 9. Reed E: Platinum-DNA adduct, nucleotide excision repair and platinum based anti-cancer chemotherapy. Cancer Treat Rev 1998;24(5):331-344. 10. Rolig RL, Lowery MP, Adair GM, Nairn RS: Characterization and analysis of Chinese hamster ovary cell ERCC1 mutant alleles. Mutagenesis 1998;13(4):357-365. 11. Li Q, Tsang B, Bostick-Bruton F, Reed E: Modulation of excision repair cross complementation group 1 (ERCC-1) mRNA expression by pharmacological agents in human ovarian carcinoma cells. Biochem Pharmacol 1999;57(4):347-353. 12. Miura M, et al. Exp Cell Res 1996;226:126-132.