Rabbit anti Human Histone H2A.x (S140)
X2754P
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetH2AX
Overview
- SupplierNordic-MUbio
- Product NameRabbit anti Human Histone H2A.x (S140)
- Delivery Days Customer7
- Application Supplier NoteAntibody can be used for immunohistochemical staining (1-5 microg/ml). Optimal concentration should be evaluated by serial dilutions.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- Applications SupplierEnzyme Immunoassay;Western Blotting;Immunohistochemistry;Enzyme Immunoassay;Western Blotting
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ClonalityPolyclonal
- Gene ID3014
- Target nameH2AX
- Target descriptionH2A.X variant histone
- Target synonymsH2A histone family member X; H2A.X; H2A/X; H2AFX; H2AX histone; histone H2A.x; histone H2AX
- HostRabbit
- IsotypeIgG
- Protein IDP16104
- Protein NameHistone H2AX
- Scientific DescriptionH2AFX; H2AX
- Shelf life instructionSee expiration date on vial
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteSynthetic peptide derived from human histone H2a.x protein. Sequence is unphosphorylated version of peptide used for Cat. No. X2752P
- UNSPSC12352203
References
- 1. Paull, T.T., et al. ‘A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage’ Curr. Biol., 10, 886-895 (2000) 2. Kobayashi, J., et al. ‘NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain.’ Curr. Biol., 12, 1846-1851 (2002) 3. Stewart, G.S., et al. ‘MDC1 is a mediator of the mammalian DNA damage checkpoint.’ Nature, 421, 961-966 (2003) 4. Lukas, C., et al. ‘Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention.’ EMBO J., 23, 2674-2683 (2004)