Rabbit anti Human Sphingosine 1 Phosphate Receptor 1 (EDG-1) CT
X1093P
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetS1PR1
Overview
- SupplierNordic-MUbio
- Product NameRabbit anti Human Sphingosine 1 Phosphate Receptor 1 (EDG-1) CT
- Delivery Days Customer7
- Application Supplier NoteDetects EDG1 receptors at concentration of 5-10 microg/ml by Western blot using a human EDG1 receptor transfected cell line. Detects an approximately 44 kDa band in RH7777 cells transfected with full length human EDG1. Due to low expression of EDG receptors, we recommend use of Pierce Femto Signal substrate for western blot development. Optimal concentration should be evaluated by serial dilutions.
- ApplicationsWestern Blot
- Applications SupplierWestern Blotting;Western Blotting
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1901
- Target nameS1PR1
- Target descriptionsphingosine-1-phosphate receptor 1
- Target synonymsCD363; CHEDG1; D1S3362; ECGF1; EDG1; EDG-1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; S1P receptor 1; S1P receptor Edg-1; S1P1; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; sphingosine 1-phosphate receptor Edg-1
- HostRabbit
- IsotypeIgG
- Protein IDP21453
- Protein NameSphingosine 1-phosphate receptor 1
- Scientific DescriptionEndothelial cell differentiation gene 1 C-terminal
- Shelf life instructionSee expiration date on vial
- ReactivityHuman, Mouse, Rat
- Reactivity SupplierHuman;Mouse;Rat
- Reactivity Supplier NoteSynthetic peptide derived from the C-terminal of the EDG-1 receptor
- UNSPSC12352203
References
- 1. Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. Liu, Y., et al., J. Clin. Invest., 2000, 106, 951-961. 2. Expression and characterization of edg-1 receptors in rat cardiomyocytes calcium deregulation in response to sphingosine-1-phosphate. Nakajima, N., et al., Eur. J. Biochem., 2000, 267, 5679-5686. 3. Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. Goetzl, E.J. and An, S.,FASEB J., 12(15), 1589-1598 (1998).