Rad21 antibody
GTX106012
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRAD21
Overview
- SupplierGeneTex
- Product NameRad21 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.38 mg/ml
- ConjugateUnconjugated
- Gene ID5885
- Target nameRAD21
- Target descriptionRAD21 cohesin complex component
- Target synonymsCDLS4; double-strand-break repair protein rad21 homolog; hHR21; HR21; HRAD21; kleisin; MCD1; MGS; nuclear matrix protein 1; NXP1; NXP-1; protein involved in DNA double-strand break repair; RAD21 homolog; SCC1; SCC1 homolog; sister chromatid cohesion 1
- HostRabbit
- IsotypeIgG
- Protein IDO60216
- Protein NameDouble-strand-break repair protein rad21 homolog
- Scientific DescriptionThe protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues. Bartosovic M et al., 2021 Jul, Nat BiotechnolRead more
- Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells. Ochiai H et al., 2020 Jun, Sci AdvRead more
- Transcription Elongation Can Affect Genome 3D Structure. Heinz S et al., 2018 Sep 6, CellRead more
- RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stress. Gatei M et al., 2014 Aug 15, Hum Mol GenetRead more