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Rad21 antibody

GTX106012
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRAD21
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Overview

  • Supplier
    GeneTex
  • Product Name
    Rad21 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.38 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5885
  • Target name
    RAD21
  • Target description
    RAD21 cohesin complex component
  • Target synonyms
    CDLS4; double-strand-break repair protein rad21 homolog; hHR21; HR21; HRAD21; kleisin; MCD1; MGS; nuclear matrix protein 1; NXP1; NXP-1; protein involved in DNA double-strand break repair; RAD21 homolog; SCC1; SCC1 homolog; sister chromatid cohesion 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO60216
  • Protein Name
    Double-strand-break repair protein rad21 homolog
  • Scientific Description
    The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues. Bartosovic M et al., 2021 Jul, Nat Biotechnol
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  • Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells. Ochiai H et al., 2020 Jun, Sci Adv
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  • Transcription Elongation Can Affect Genome 3D Structure. Heinz S et al., 2018 Sep 6, Cell
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  • RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stress. Gatei M et al., 2014 Aug 15, Hum Mol Genet
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