Rad21 antibody
GTX106012
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetRAD21
Overview
- SupplierGeneTex
- Product NameRad21 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.38 mg/ml
- ConjugateUnconjugated
- Gene ID5885
- Target nameRAD21
- Target descriptionRAD21 cohesin complex component
- Target synonymsCDLS4, HR21, HRAD21, MCD1, MGS, NXP1, SCC1, hHR21, double-strand-break repair protein rad21 homolog, NXP-1, RAD21 homolog, SCC1 homolog, kleisin, nuclear matrix protein 1, protein involved in DNA double-strand break repair, sister chromatid cohesion 1
- HostRabbit
- IsotypeIgG
- Protein IDO60216
- Protein NameDouble-strand-break repair protein rad21 homolog
- Scientific DescriptionThe protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Bartosovic M, Kabbe M, Castelo-Branco G. Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues. Nat Biotechnol. 2021,39(7):825-835. doi: 10.1038/s41587-021-00869-9Read this paper
- Ochiai H, Hayashi T, Umeda M, et al. Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells. Sci Adv. 2020,6(25):eaaz6699. doi: 10.1126/sciadv.aaz6699Read this paper
- Heinz S, Texari L, Hayes MGB, et al. Transcription Elongation Can Affect Genome 3D Structure. Cell. 2018,174(6):1522-1536.e22. doi: 10.1016/j.cell.2018.07.047Read this paper
- Gatei M, Kijas AW, Biard D, et al. RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stress. Hum Mol Genet. 2014,23(16):4232-48. doi: 10.1093/hmg/ddu141Read this paper





![WB analysis of HEK293 cell lysate using GTX30641 Rad21 antibody [CM110-2C10].](https://www.genetex.com/upload/website/prouct_img/normal/GTX30641/GTX30641_1448_WB_w_23060722_906.webp)
