Rad52 antibody [5H9]
GTX70301
Overview
- SupplierGeneTex
- Product NameRad52 antibody [5H9]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5H9
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID5893
- Target nameRAD52
- Target descriptionRAD52 homolog, DNA repair protein
- Target synonymsDNA repair protein RAD52 homolog; recombination protein RAD52; rhabdomyosarcoma antigen MU-RMS-40.23
- HostMouse
- IsotypeIgG1
- Protein IDP43351
- Protein NameDNA repair protein RAD52 homolog
- Scientific DescriptionThe protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- DNA damage responses in human induced pluripotent stem cells and embryonic stem cells. Momcilovic O et al., 2010 Oct 15, PLoS OneRead more
- The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells. de Souza-Pinto NC et al., 2009 Aug, Mol Cell BiolRead more
- MicroRNA regulation of DNA repair gene expression in hypoxic stress. Crosby ME et al., 2009 Feb 1, Cancer ResRead more