Radicicol
HY-N6769
Overview
- SupplierMedChem Express
- Product NameRadicicol [12772-57-5]
- Delivery Days Customer10
- CAS Number12772-57-5
- CertificationResearch Use Only
- Estimated Purity99.63
- Molecular FormulaC18H17ClO6
- Molecular Weight364.78
- Scientific DescriptionRadicicol is an inhibitor of Hsp90 with an IC50 value [1]. Radicicol exhibits inhibition on PDK with IC50s of 230 microM (PDK1) and 400 microM (PDK3). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB[2]. Radicicol is also an inhibitor of fat mass and obesity-associated protein (FTO), with an IC50 value of 16.04 microM[3].
- SMILESOC1=C2C(CC(/C=C/C=C\[C@@H](O3)[C@H]3C[C@@H](C)OC2=O)=O)=C(Cl)C(O)=C1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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