Radicicol
HY-N6769
Overview
- SupplierMedChem Express
- Product NameRadicicol [12772-57-5]
- Delivery Days Customer10
- CAS Number12772-57-5
- CertificationResearch Use Only
- Estimated Purity99.63
- Molecular FormulaC18H17ClO6
- Molecular Weight364.78
- Scientific DescriptionRadicicol is an inhibitor of Hsp90 with an IC 50 value [1] . Radicicol exhibits inhibition on PDK with IC 50 s of 230 microM ( PDK1 ) and 400 microM ( PDK3 ). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB [2] . Radicicol is also an inhibitor of fat mass and obesity-associated protein ( FTO ), with an IC 50 value of 16.04 microM [3] .
- SMILESOC1=C2C(CC(/C=C/C=C\[C@@H](O3)[C@H]3C[C@@H](C)OC2=O)=O)=C(Cl)C(O)=C1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200