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Radicicol

HY-N6769
MedChem Express
CAS Number12772-57-5
Product group Chemicals
Estimated Purity99.63
Molecular Weight364.78
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Radicicol [12772-57-5]
  • Delivery Days Customer
    10
  • CAS Number
    12772-57-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.63
  • Molecular Formula
    C18H17ClO6
  • Molecular Weight
    364.78
  • Scientific Description
    Radicicol is an inhibitor of Hsp90 with an IC 50 value [1] . Radicicol exhibits inhibition on PDK with IC 50 s of 230 microM ( PDK1 ) and 400 microM ( PDK3 ). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB [2] . Radicicol is also an inhibitor of fat mass and obesity-associated protein ( FTO ), with an IC 50 value of 16.04 microM [3] .
  • SMILES
    OC1=C2C(CC(/C=C/C=C\[C@@H](O3)[C@H]3C[C@@H](C)OC2=O)=O)=C(Cl)C(O)=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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