Radicicol [12772-57-5]
T16719
Overview
- SupplierTargetMol Chemicals
- Product NameRadicicol [12772-57-5]
- Delivery Days Customer44
- CAS Number12772-57-5
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameRadicicol
- Molecular FormulaC18H17ClO6
- Molecular Weight364.78
- Scientific DescriptionRadicicol is an antifungal antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is an inhibitor of Hsp90 (IC50: 1 microM). Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients, leading to proteasomal degradation.
- Shelf life instruction3 years
- SMILES[H][C@@]12C[C@@H](C)OC(=O)c3c(O)cc(O)c(Cl)c3CC(=O)\C=C\C=C/[C@@]1([H])O2
- Storage Instruction-20°C
- UNSPSC12352200
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