Dot Blot analysis of Raf1 phospho- or Non phospho-peptide using GTX30714 Raf1 (phospho Ser43) antibody. 50ng of Phospho-peptide or Non phospho-peptide per dot were adsorbed. Dilution : 0.5microg/ml
Dot Blot analysis of Raf1 phospho- or Non phospho-peptide using GTX30714 Raf1 (phospho Ser43) antibody. 50ng of Phospho-peptide or Non phospho-peptide per dot were adsorbed. Dilution : 0.5microg/ml
Raf1 (phospho Ser43) antibody
GTX30714
Overview
- SupplierGeneTex
- Product NameRaf1 (phospho Ser43) antibody
- Delivery Days Customer9
- ApplicationsDot Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5894
- Target nameRAF1
- Target descriptionRaf-1 proto-oncogene, serine/threonine kinase
- Target synonymsCMD1NN; CRAF; c-Raf; C-Raf proto-oncogene, serine/threonine kinase; NS5; Oncogene RAF1; proto-oncogene c-RAF; raf proto-oncogene serine/threonine protein kinase; RAF proto-oncogene serine/threonine-protein kinase; Raf-1; v-raf-1 murine leukemia viral oncogene homolog 1; v-raf-1 murine leukemia viral oncogene-like protein 1
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionThis gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203