RALA Antibody

Cusabio

RALA Antibody

20

ImmunoFluorescence, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

RALA

RAS like proto-oncogene A

HINCONS, RAL, ras-related protein Ral-A, RALA Ras like proto-oncogene A, RAS-like protein A, Ras family small GTP binding protein RALA, ras related GTP binding protein A, v-ral simian leukemia viral oncogene homolog A (ras related)

Rabbit

IgG

Ras-related protein Ral-A

Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.

Human

-20°C or -80°C

41116161