RBPJK antibody [C1C3]

GeneTex

RBPJK antibody [C1C3]

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

0.75 mg/ml

Unconjugated

RBPJ

recombination signal binding protein for immunoglobulin kappa J region

AOS3; CBF1; CBF-1; csl; H-2K binding factor-2; IGKJRB; IGKJRB1; immunoglobulin kappa J region recombination signal binding protein 1; KBF2; RBP-J; RBP-J kappa; RBPJK; RBP-JK; RBPSUH; recombining binding protein suppressor of hairless; renal carcinoma antigen NY-REN-30; SUH; suppressor of hairless homolog

Rabbit

IgG

Recombining binding protein suppressor of hairless

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.

Human

-20°C or -80°C,2°C to 8°C

12352203