Regorafenib (mesylate)
HY-10331B
CAS Number835621-08-4
Product group Chemicals
Molecular Weight578.92
Overview
- SupplierMedChem Express
- Product NameRegorafenib (mesylate) [835621-08-4]
- Delivery Days Customer10
- CAS Number835621-08-4
- CertificationResearch Use Only
- Molecular FormulaC22H19ClF4N4O6S
- Molecular Weight578.92
- Scientific DescriptionRegorafenib (BAY 73-4506) mesylate is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC 50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3 , PDGFRbeta , Kit , RET and Raf-1 , respectively. Regorafenib mesylate shows very robust antitumor and antiangiogenic activity [1] .
- SMILESO=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(OC3=CC(C(NC)=O)=NC=C3)C=C2F.CS(O)(=O)=O
- UNSPSC12352200