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Regorafenib mesylate [835621-08-4]

Regorafenib mesylate [835621-08-4]

T64090
TargetMol Chemicals
CAS Number835621-08-4
DownloadMSDS
Product group Chemicals
Molecular Weight578.92
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Regorafenib mesylate [835621-08-4]
  • Delivery Days Customer
    72
  • CAS Number
    835621-08-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Regorafenib mesylate
  • Molecular Formula
    C22H19ClF4N4O6S
  • Molecular Weight
    578.92
  • Scientific Description
    Regorafenib (BAY 73-4506) mesylate is an orally active multi-target receptor tyrosine kinase inhibitor, inhibiting VEGFR1/2/3 (IC50=13/4.2/46 nM), PDGFRbeta (IC50: 22 nM), Kit (IC50: 7 nM), RET (IC50: 1.5 nM), and Raf-1 (IC50: 2.5 nM), with potent anti-tumor and anti-angiogenic effects.
  • Shelf life instruction
    3 years
  • SMILES
    CS(O)(=O)=O.CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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Chemical Structure
Product group Chemicals
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