RepSox

MedChem Express

RepSox [446859-33-2]

10

446859-33-2

Research Use Only

99.92

C17H13N5

287.32

RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-beta-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC 50 value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes [1] [2] .

CC1=NC(C2=NNC=C2C3=NC4=CC=CN=C4C=C3)=CC=C1

-20°C,2°C to 8°C

12352200