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RepSox [446859-33-2]

RepSox [446859-33-2]

T6337
TargetMol Chemicals
CAS Number446859-33-2
DownloadMSDS
Product group Chemicals
Estimated Purity99.62%
Molecular Weight287.32
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    RepSox [446859-33-2]
  • Delivery Days Customer
    4
  • CAS Number
    446859-33-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    RepSox
  • Estimated Purity
    99.62%
  • Molecular Formula
    C17H13N5
  • Molecular Weight
    287.32
  • Scientific Description
    RepSox (ALK5 Inhibitor II) is a TGFbetaR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM). RepSox induces adipogenesis in MEFs cells.
  • Shelf life instruction
    3 years
  • SMILES
    Cc1cccc(n1)-c1n[nH]cc1-c1ccc2ncccc2n1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • TGFbetaR-1/ALK5 inhibitor RepSox induces enteric glia-to-neuron transition and influences gastrointestinal mobility in adult mice. Shi CJ et al., 2023 Jan, Acta Pharmacol Sin
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