Effect of Resistin (human) (rec.) (AG-40A-0010Y) on glucose uptake in L6 cells. Inhibition of insulin-stimulated glucose uptake in L6 skeletal muscle cells by resistin (as expected: 1microg/ml). Rat myoblasts (L6) were cultured and differentiated into myotub
Resistin (human) (rec.)
AG-40A-0010Y
Overview
- SupplierAdipoGen Life Sciences
- Product NameResistin (human) (rec.)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity>95%
- Protein IDQ9HD89
- Protein NameResistin
- Scientific DescriptionProtein. Human resistin (aa 19-108) is fused at the N-terminus to a FLAG®-tag. Source: HEK 293 cells. Endotoxin content: <0.01EU/microg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Purity: >95% (SDS-PAGE). The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELM-alpha/FIZZ 1 and RELM-beta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM. - The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELM-alpha/FIZZ 1 and RELM-beta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352202