RFC2 antibody
GTX105087
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetRFC2
Overview
- SupplierGeneTex
- Product NameRFC2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.43 mg/ml
- ConjugateUnconjugated
- Gene ID5982
- Target nameRFC2
- Target descriptionreplication factor C subunit 2
- Target synonymsA1 40 kDa subunit; activator 1 subunit 2; replication factor C (activator 1) 2, 40kDa; replication factor C subunit 2; RF-C 40 kDa subunit; RFC40
- HostRabbit
- IsotypeIgG
- Protein IDP35250
- Protein NameReplication factor C subunit 2
- Scientific DescriptionThe elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of this gene has been associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Xanthohumol regulates miR-4749-5p-inhibited RFC2 signaling in enhancing temozolomide cytotoxicity to glioblastoma. Ho KH et al., 2020 Aug 1, Life SciRead more