RFXANK antibody

GeneTex

RFXANK antibody

9

Reacts with residues 18-31 [ASELGDPEDPGEEAC] of the RFX-B protein.

Western Blot, ELISA

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

RFXANK

regulatory factor X associated ankyrin containing protein

ANKRA1; ankyrin repeat family A protein 1; ankyrin repeat-containing regulatory factor X-associated protein; BLS; DNA-binding protein RFXANK; F14150_1; regulatory factor X subunit B; RFX-B; RFX-Bdelta4

Rabbit

IgG

DNA-binding protein RFXANK

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013]

Human, Primate

-20°C or -80°C,2°C to 8°C

12352203