Rigosertib [592542-59-1]

TargetMol Chemicals

Rigosertib [592542-59-1]

4

592542-59-1

Chemical

Research Use Only

Rigosertib

0.9733

C21H25NO8S

451.49

Rigosertib (ON-01910) is a selective, non-ATP-competitive PLK1 inhibitor (IC50: 9 nM) and multi-kinase inhibitor. As a selective anti-cancer agent, Rigosertib induces apoptosis by inhibiting the PI3 kinase/Akt pathway, promotes histone H2AX phosphorylation, and induces G2/M arrest in the cell cycle.

3 years

C(=C/S(CC1=CC(NCC(O)=O)=C(OC)C=C1)(=O)=O)\C2=C(OC)C=C(OC)C=C2OC

-20°C

12352200