RIN1 antibody
GTX131627
Overview
- SupplierGeneTex
- Product NameRIN1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.67 mg/ml
- ConjugateUnconjugated
- Gene ID9610
- Target nameRIN1
- Target descriptionRas and Rab interactor 1
- Target synonymsras and Rab interactor 1; ras inhibitor 1; ras inhibitor JC99; ras inhibitor RIN1; ras interaction/interference protein 1
- HostRabbit
- IsotypeIgG
- Protein IDQ13671
- Protein NameRas and Rab interactor 1
- Scientific DescriptionRas effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203