Rineterkib

AbMole BioScience

Rineterkib

9

1715025-32-3

Chemical

Research Use Only

C26H27BrF3N5O2

578.42

Rineterkib (compound B) is an orally active inhibitor of ERK1/2 that exerts an antiproliferative effect by activating mutations in the MAPK pathway. This activity is particularly associated with KRAS-mutant non-small cell lung cancer, BRAF-mutant non-small cell lung cancer, KRAS-mutant pancreatic cancer, KRAS-mutant colon cancer, and KRAS-mutant ovarian cancer.

4°C, protect from light, dry

12352200