The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA870281(RNF20 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA870281(RNF20 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200)
RNF20 Antibody
CSB-PA870281
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetRNF20
Overview
- SupplierCusabio
- Product NameRNF20 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID56254
- Target nameRNF20
- Target descriptionring finger protein 20
- Target synonymsBRE1; BRE1 E3 ubiquitin ligase homolog; BRE1A; E3 ubiquitin-protein ligase BRE1A; hBRE1; homolog of S. cerevisiae BRE1; RING-type E3 ubiquitin transferase BRE1A
- HostRabbit
- IsotypeIgG
- Protein IDQ5VTR2
- Protein NameE3 ubiquitin-protein ligase BRE1A
- Scientific DescriptionThe protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203