Ro 31-8220 Mesylate

AbMole BioScience

Ro 31-8220 Mesylate

9

138489-18-6

Chemical

Research Use Only

>99.0%

C25H23N5O2S.CH4O3S

553.65

Ro 31-8220 is a pan-PKC inhibitor with IC50 of 5 nM, 24 nM, 14 nM, 27 nM, and 24 nM for PKC-alfa, PKC-bètaI, PKC-bètaII, PKC-gamma, and PKC-epsilon, respectively, and also shows potent inhibition against MAPKAP-K1b, MSK1, GSK3bèta and S6K1.

C[N]1C=C(C2=CC=CC=C12)C3=C(C(=O)NC3=O)C4=C[N](CCCSC(N)=N)C5=CC=CC=C45.C[S](O)(=O)=O

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