Bisindolylmaleimide IX . methansulfonate [Ro 31-8220] [138489-18-6]

AdipoGen Life Sciences

Bisindolylmaleimide IX . methansulfonate [Ro 31-8220]

10

138489-18-6

Research Use Only

>98%

C25H23N5O2S . CH4O3S

457.6 . 96.1

Chemical. CAS: 138489-18-6. Formula: C25H23N5O2S . CH4O3S. MW: 457.6 . 96.1. Selective and cell permeable protein kinase C (PKC) inhibitor. Inhibits the stimulation of insulin secretion by glucose. Inhibits T cell activation. Apoptosis inducer. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Transcription inhibitor. Induces TNF receptor family-mediated cell death. Pim-1 kinase inhibitor. Antitumor compound. - Selective and cell permeable protein kinase C (PKC) inhibitor [1, 2, 3]. Inhibits the stimulation of insulin secretion by glucose [4, 11]. Inhibits T cell activation [5]. Apoptosis inducer [6, 8, 9,10, 13]. Potent glycogen synthase kinase-3 (GSK-3) inhibitor [7]. Transcription inhibitor [9]. Induces TNF receptor family-mediated cell death [10]. Pim-1 kinase inhibitor [12]. Antitumor compound [13].

CS(O)(=O)=O.CN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CN(CCCSC(N)=N)C2=C1C=CC=C2

-20°C,2°C to 8°C

51202000