RO 46-8443 [175556-12-4]

TargetMol Chemicals

RO 46-8443 [175556-12-4]

4

175556-12-4

Research Use Only

RO 46-8443

98.50%

C31H35N3O8S

609.69

RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition.

3 years

COc1ccc(cc1)-c1nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c(Oc2ccccc2OC)c(OC[C@H](O)CO)n1

-20°C

12352200