Rolapitant (hydrochloride) [858102-79-1]
HY-14751A
CAS Number858102-79-1
Product group Chemicals
Molecular Weight536.94
Overview
- SupplierMedChem Express
- Product NameRolapitant (hydrochloride) [858102-79-1]
- Delivery Days Customer10
- CAS Number858102-79-1
- CertificationResearch Use Only
- Molecular FormulaC25H27ClF6N2O2
- Molecular Weight536.94
- Scientific DescriptionRolapitant (SCH619734) hydrochloride is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant hydrochloride does not interact with CYP3A4. Rolapitant hydrochloride shows potent anti-emetic activity in a ferret emesis model[1][2].
- SMILESO=C1N[C@]2(CN[C@@](C3=CC=CC=C3)(CO[C@@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)CC2)CC1.[H]Cl
- UNSPSC12131703
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