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Rolapitant hydrochloride [858102-79-1]

Rolapitant hydrochloride [858102-79-1]

T3724
TargetMol Chemicals
CAS Number858102-79-1
Product group Chemicals
Estimated Purity98.46%
Molecular Weight536.94
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Rolapitant hydrochloride
  • Delivery Days Customer
    4
  • CAS Number
    858102-79-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Rolapitant hydrochloride
  • Estimated Purity
    98.46%
  • Molecular Formula
    C25H27ClF6N2O2
  • Molecular Weight
    536.94
  • Scientific Description
    Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting, and orally active neurokinin 1 (NK1) receptor antagonist with a K_i of 0.66 nM, which does not interact with CYP3A4 and demonstrates potent centrally-mediated anti-emetic activity in both acute and delayed ferret emesis models [1] [2].
  • Shelf life instruction
    3 years
  • SMILES
    Cl.C[C@@H](OC[C@]1(CC[C@]2(CCC(=O)N2)CN1)c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200