Immunofluorescence staining of Hela cells with CSB-PA020072LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunofluorescence staining of Hela cells with CSB-PA020072LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
ROS1 Antibody
CSB-PA020072LA01HU
ApplicationsImmunoFluorescence, ELISA
Product group Antibodies
ReactivityHuman
TargetROS1
Overview
- SupplierCusabio
- Product NameROS1 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6098
- Target nameROS1
- Target descriptionROS proto-oncogene 1, receptor tyrosine kinase
- Target synonymsc-ros oncogene 1 , receptor tyrosine kinase; c-ros-1; MCF3; proto-oncogene c-Ros-1; proto-oncogene tyrosine-protein kinase ROS; ROS; ROS proto-oncogene 1 , receptor tyrosine kinase; transmembrane tyrosine-specific protein kinase; v-ros avian UR2 sarcoma virus oncogene homolog 1
- HostRabbit
- IsotypeIgG
- Protein IDP08922
- Protein NameProto-oncogene tyrosine-protein kinase ROS
- Scientific DescriptionOrphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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