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RPS6 antibody

GTX113542
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetRPS6
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Overview

  • Supplier
    GeneTex
  • Product Name
    RPS6 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.55 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6194
  • Target name
    RPS6
  • Target description
    ribosomal protein S6
  • Target synonyms
    40S ribosomal protein S6; phosphoprotein NP33; S6; small ribosomal subunit protein eS6
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP62753
  • Protein Name
    40S ribosomal protein S6
  • Scientific Description
    Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Spatial organization and function of RNA molecules within phase-separated condensates are controlled by Dnd1.
    Read more
  • Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice.
    Read more
  • Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes. Kim A et al., 2021 Dec, J Cachexia Sarcopenia Muscle
    Read more
  • Rhapontigenin inhibits TGF-beta-mediated epithelial-mesenchymal transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1alpha degradation. Yeh YH et al., 2016 May, Oncol Rep
    Read more
  • Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition EMT in zebrafish. Chen CH et al., 2014 Aug 15, Oncotarget
    Read more
  • Activation of the mTOR pathway by low levels of xenoestrogens in breast epithelial cells from high-risk women. Goodson WH 3rd et al., 2011 Nov, Carcinogenesis
    Read more

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