RS-25344 hydrochloride

Biorbyt

RS-25344 hydrochloride [152815-28-6]

10

152815-28-6

Research Use Only

C19H14ClN5O4

415.83

RS-25344 HCl is a potent and selective phosphodiesterase (PDE) 4 inhibitor (IC50 values are 0.28, > 100, 160 and 330 nM at PDE4, PDE1, PDE2 and PDE3 respectively). It inhibits eosinophil chemotaxis and increases progressive motility of spermatozoa in vitro.

[H]Cl.O=C1N(C2=CC=CC([N+]([O-])=O)=C2)C3=NC=CC=C3C(N1CC4=CC=NC=C4)=O

12352200