IHC-P analysis of human lung cancer (left) and breast cancer (right) using GTX83372 RTN3 antibody [10A8].
![IHC-P analysis of human Liver tissue using GTX83372 RTN3 antibody [10A8].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83372/GTX83372_20170912_IHC-P_w_23061322_449.webp "IHC-P analysis of human Liver tissue using GTX83372 RTN3 antibody [10A8].")
IHC-P analysis of human lung cancer (left) and breast cancer (right) using GTX83372 RTN3 antibody [10A8].
RTN3 antibody [10A8]
GTX83372
ApplicationsImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetRTN3
Overview
- SupplierGeneTex
- Product NameRTN3 antibody [10A8]
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10A8
- ConjugateUnconjugated
- Gene ID10313
- Target nameRTN3
- Target descriptionreticulon 3
- Target synonymsASY interacting protein; ASYIP; HAP; homolog of ASY protein; neuroendocrine-specific protein-like 2; neuroendocrine-specific protein-like II; NSPL2; NSPLII; NSP-like protein 2; NSP-like protein II; reticulon-3; RTN3-A1
- HostMouse
- IsotypeIgG2a
- Protein IDO95197
- Protein NameReticulon-3
- Scientific DescriptionThis gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Arl6IP1 has the ability to shape the mammalian ER membrane in a reticulon-like fashion. Yamamoto Y et al., 2014 Feb 15, Biochem JRead more
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